Chiral Separation of Racemic Thiols Based on Diastereomer Formation with a Fluorescent Chiral Tagging Reagent by Reversed-Phase Liquid Chromatography.
نویسندگان
چکیده
منابع مشابه
Enantiomeric separation of Linezolid by chiral reversed-phase liquid chromatography.
A chiral liquid chromatographic method is developed for the enantiomeric resolution of Linezolid, (S)(-)-N-[[-3-(3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] acetamide, an antibiotic in bulk drugs. The enantiomers of Linezolid are resolved on a Chiralcel OJ-RH column using a mobile phase system containing 150mM di-sodium hydrogen phosphate buffer (pH 4.5)-acetonitrile (86:14,...
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To perform chiral separation of three flavonoid racemates, including dihydrodaidzein, equol and alpinetin, a simple and effective method was developed by using sulfobutyl ether-beta-cyclodextrin (SBE-beta-CD) as a mobile phase additive in HPLC system. The effects of different factors on the chiral separation were investigated, including cyclodextrin (CD) types (alpha-CD, gamma-CD, beta-CD, meth...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 1997
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.13.113